BAPTA tetrapotassium

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

73630-08-7

包装与价格：

包装	价格(元)
1g	电议
5g	电议
10g	电议

产品介绍

BAPTA tetrapotassium 是一种选择性的钙离子螯合剂。BAPTA 作为钙离子指示剂，对镁离子和钙离子有较高的选择性。BAPTA tetrapotassium 被广泛用作细胞内缓冲液，用于研究通过质膜 Ca2+ 透性通道从细胞内存储或内流 Ca2+ 释放的影响。BAPTA tetrapotassium 还可抑制磷脂酶 C (phospholipase C) 的活性，与其钙离子螯合特性无关。

Cas No.	73630-08-7
别名	BAPTA四钾盐
分子式	C₂₂H₂₀K₄N₂O₁₀
分子量	628.79
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	BAPTA tetrapotassium is a selectivechelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrapotassium is widely used as an intracellular buffer for investigating the effects of Ca²⁺release from intracellular stores or influx via Ca²⁺-permeable channels in the plasma membrane. BAPTA tetrapotassium can also inhibitphospholipase Cactivity independently of their role as Ca²⁺chelators^[1]^[2]^[4]. BAPTA (0.3-30 μM; 1 h) can be used for the prevention of [Ca²⁺]-induced cell damage, but disturbe calcium signalling in isingle differentiated NH15-CA2 neuroblastoma and glioma hybrid cells^[3]. BAPTA (0-10 mM) inhibits phospholipase C (PLC) activity in a dose-dependent manner, and is unrelated to Ca²⁺^[2]. [1]. R Y Tsien, et al. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry. 1980 May 27;19(11):2396-404. [2]. Roger C Hardie, et al. Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid (BAPTA) and di-bromo BAPTA. Cell Calcium. 2005 Dec;38(6):547-56. [3]. M B Collatz, et al. Intracellular calcium chelator BAPTA protects cells against toxic calcium overload but also alters physiological calcium responses. Cell Calcium