生物活性
WAY-100635 maleate salt是一种有效的、选择性的5-羟色胺1A拮抗剂,对5-HT的IC50为0.95-0.12 nM。
化学数据
目录号 | A15282 |
作用机制 | Antagonist (拮抗剂) |
M. Wt | 538.64 |
Formula | C29H38N4O6 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 634908-75-1 |
Synonyms | WAY 100635 maleate salt, WAY100635 maleate salt |
SMILES | COC1=CC=CC=C1N2CCN(CC2)CCN(C3=CC=CC=N3)C(=O)C4CCCCC4.C(=CC(=O)O)C(=O)O |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 18.57 mL | 92.83 mL | 185.65 mL |
0.5 mM | 3.71 mL | 18.57 mL | 37.13 mL |
1 mM | 1.86 mL | 9.28 mL | 18.57 mL |
5 mM | 0.37 mL | 1.86 mL | 3.71 mL |
*The above data is based on the productmolecular weight 538.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.