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Guanosine 5'-diphosphate sodium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Guanosine 5'-diphosphate sodium图片
CAS NO:43139-22-6
包装与价格:
包装价格(元)
10mg电议
50mg电议
250mg电议

产品介绍
Guanosine 5'-diphosphate (GDP) sodium 是一种核苷二磷酸,可激活 5'-三磷酸腺苷敏感的 K+ 通道。Guanosine 5'-diphosphate sodium 是一种潜在的铁动员剂,可阻断铁调素-铁转运蛋白 (hepcidin-ferroportin ) 相互作用并调节 IL-6/stat-3 通路。Guanosine 5'-diphosphate sodium 可用于炎症研究,如炎症性贫血 (AI)。
Cas No.43139-22-6
别名GDP sodium
分子式C10H15N5NaO11P2
分子量466.19
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitiveK+channel. Guanosine 5'-diphosphate sodium is a potential iron mobilizer, which prevents thehepcidin-ferroportininteraction and modulates theinterleukin-6 (IL-6)/stat-3pathway. Guanosine 5'-diphosphate sodium can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2].

[1]. S Kajioka, et al. Guanosine diphosphate activates an adenosine 5'-triphosphate-sensitive K+ channel in the rabbit portal vein. J Physiol. 1991 Dec;444:397-418.
[2]. Angmo S, et al. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 Jan 5;7:40097.