Cilansetron, formerly known as DU-123265, KC-9946, is a 5-HT3 antagonist potentially for the treatment of irritable bowel syndrome. Cilansetron acts at its site of absorption to antagonize the sensitivity of mesenteric afferent fibres to 5-hydroxytryptamine in the rat jejunum. References: Painsipp E, Shahbazian A, Holzer P. Alosetron, cilansetron and tegaserod modify mesenteric but not colonic blood flow in rats. Br J Pharmacol. 2009 Nov;158(5):1210-26. doi: 10.1111/j.1476-5381.2009.00392.x. Epub 2009 Sep 25. PubMed PMID: 19785647; PubMed Central PMCID: PMC2782331.

纯度：≥98%

CAS：120635-74-7