CL-184005 is a platelet activating factor (PAF) inhibitor potentially for the treatment of gram-negative bacterial infection and septic shock. CL-184005 interferes with tumor necrosis factor synthesis induced by S. aureus. Spleen-associated tumor necrosis factor protein was also decreased by pretreatment with CL-184005. References: Negro Alvarez JM, Miralles López JC, Ortiz Martínez JL, Abellán Alemán A, Rubio del Barrio R. Platelet-activating factor antagonists. Allergol Immunopathol (Madr). 1997 Sep-Oct;25(5):249-58. Review. PubMed PMID: 9395010.

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CAS：140466-18-8