CAS NO: | 66514-99-6 |
规格: | ≥98% |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
1g | 电议 |
Description: (S)-Baclofen, the S-isomer of baclofen(also known as STX 209) which is a derivative of gamma-aminobutyric acid and a selective GABAB receptor agonist.primarily used to treat spasticity. Baclofen is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing It acts at spinal and supraspinal sites, reducing excitatory transmission. GABAB receptors are metabotropic receptors which produce slow inhibitory signals. (S)-Baclofen has effects on excitation in the ascending auditory pathway making it a potential treatment for hyperactive auditory disorders such as tinnitus and hyperacusis. References: Neuroscience. 2014 Jan 31;258:410-21. doi: 10.1016/j.neuroscience.2013.11.032. Epub 2013 Nov 26. PubMed PMID: 24291770; J Neurochem. 1986 Sep;47(3):898-903; Lancet. 1984 May 12;1(8385):1078. Related CAS No.: 63701-55-3 [(R)-Baclofen HCl]
纯度:≥98%
CAS:66514-99-6