CM-TPMF is a subtype-selective activator of K(Ca)2.1. The K(Ca)2.1 selectivity of (-)-CM-TPMF depends critically on Ser293 as revealed by loss- and gain-of-function mutations. References: Hougaard C, Hammami S, Eriksen BL, Sorensen US, Jensen ML, Strobaek D, Christophersen P. Evidence for a common pharmacological interaction site on K(Ca)2 channels providing both selective activation and selective inhibition of the human K(Ca)2.1 subtype. Mol Pharmacol. 2012 Feb;81(2):210-9. doi: 10.1124/mol.111.074252. Epub 2011 Nov 1. PubMed PMID: 22046005.

纯度：≥98%

CAS：477865-59-1