Collagen type IV alpha1 (531-543) is a protein that in humans is encoded by the COL4A1 gene on chromosome 13. It is ubiquitously expressed in many tissues and cell types. COL4A1 is a subunit of the type IV collagen and plays a role in angiogenesis. Mutations in the gene have been linked to diseases of the brain, muscle, kidney, eye, and cardiovascular system. The COL4A1 gene also contains one of 27 SNPs associated with increased risk of coronary artery disease. It is active in directly promoting keratinocyte adhesion. References: Wilke MS, Furcht LT. Human keratinocytes adhere to a unique heparin-binding peptide sequence within the triple helical region of type IV collagen. J Invest Dermatol. 1990 Sep;95(3):264-70. PubMed PMID: 2384687.

纯度：≥98%

CAS：119953-02-5