Description: Cyclovirobuxine D HCl (CVB-D; Bebuxine) is a natural compound isolated from Buxus microphylla, which has been used for treating acute myocardial ischemia. Cyclovirobuxine D an alkaloid component in a traditional Chinese herb, could induce autophagy in the MCF-7 human breast cancer cell line. It has protective effect against oxidative stress and energy metabolism in rats of experimental myocardial injury induced by sympathetic overactivity. Besides, Cyclovirobuxine D is beneficial for heart failure induced by myocardial infarction and supports the potential for Cyclovirobuxine D as a new therapy for heart failure.

References: J Pharmacol Sci. 2014;125(1):74-82. Epub 2014 Apr 24.

纯度：≥98%

CAS：860-79-7 (free base)