CH-5137291 is a AR pure antagonist with AR nuclear translocation-inhibiting activity. It inhibits the growth of castration-resistant prostate cancer cells. CH5137291 offers a novel therapeutic approach against major types of castration-resistant prostate cancers. References: Ishikura N, Kawata H, Nishimoto A, Nakamura R, Tsunenari T, Watanabe M, Tachibana K, Shiraishi T, Yoshino H, Honma A, Emura T, Ohta M, Nakagawa T, Houjo T, Corey E, Vessella RL, Aoki Y, Sato H. CH5137291, an androgen receptor nuclear translocation-inhibiting compound, inhibits the growth of castration-resistant prostate cancer cells. Int J Oncol. 2015 Apr;46(4):1560-72. doi: 10.3892/ijo.2015.2860. Epub 2015 Jan 30. PubMed PMID: 25634071.

纯度：≥98%

CAS：1043446-39-4