OSI754 (also known as CP-609754, CP-609,754, LNK-754) is a novel and potent farnesyltransferase inhibitor (TFI) that has potential anticancer activity. Since farnesyltransferase is known to prevent proper functioning of Ras, a family of proteins often abnormally activated in cancer, FTIs were first developed as potential anticancer agents. A number of FTIs underwent preclinical testing but were found to have major side effects, while others entered clinical development in a variety of cancers, only to be discontinued at phase I due to a lack of efficacy.

纯度：≥98%

CAS：1190094-64-4 (free base)