Description: Cridanimod sodium, sodium salt of Cridanimod (XBIO-101; Virexxa), is a novel and potent immunomodulator and interferon inducer with antineoplastic activity. It acts as a progesterone receptor (PR) activator mediated through induction of IFNα and IFNβ expression. Cridanimod can increase progesterone receptor (PR) expression and is able to induce the expression of PR in endometrial cancer. This could increase the sensitivity of endometrial cancer cells to progestin monotherapy.