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CFI-402257 HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CFI-402257 HCl图片
CAS NO:1610677-37-6
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍

CFI-402257 HCl (CFI402257), the hydrochloride salt of CFI-402257, is a novel, highly potent, orally bioavailable and selective inhibitor of TTK protein kinase (Monopolar spindle 1 [Mps1]) with potential anticancer activity. It inhibits TTK with a Ki of 0.1 nM. TTK is an essential chromosomal regulator overexpressed in aneuploid tumors, and is important in regulating cell growth. High TTK levels correlate with a high tumor grade11 and poor patient outcomes. TTK inhibition are associated with a disabled mitotic checkpoint, resulting in chromosome segregation errors, aneuploidy, and cell death.

纯度:≥98%

CAS:1610677-37-6