Cyclo(his-pro) is a cyclic dipeptide derived from the hydrolytic removal of the amino-terminal pyroglutamic acid residue of the hypothalamic thyrotropin-releasing hormone, may be important in regulating the nature of the glial cell contribution. Cyclo(His-Pro) is ubiquitous in the central nervous system and is a key substrate of organic cation transporters, which are strongly linked to neuroprotection. Cyclo(His-Pro) has striking potential for therapeutic application by both parenteral and orally bioavailable administration routes and may represent an important new tool in counteracting neuroinflammation-based degenerative pathologies. References: Kastin AJ, Pan W. Involvement of the Blood-Brain Barrier in Metabolic Regulation. CNS Neurol Disord Drug Targets. 2016 Sep 20. [Epub ahead of print] PubMed PMID: 27658512.

纯度：≥98%

CAS：53109-32-3