Cephacetrile is a broad-spectrum first-generation cephalosporin with antibiotic and antibacterial activity. Cephacetrile binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. References: Blanc CH, Meyer-Brunot HG, Tosch W, Schelling JL. [Serum and joint levels of cefacetrile during its administration for septic arthritis]. Schweiz Med Wochenschr. 1978 Jul 1;108(26):988-94. French. PubMed PMID: 663591.

纯度：≥98%

CAS：10206-21-0