CDK12-IN-E9 is a covalent inhibitor of CDK12. It has been shown to overcome resistance to the THZ series of covalent transcriptional CDK Inhibitors. References: Gao Y, Zhang T, Terai H, Ficarro SB, Kwiatkowski N, Hao MF, Sharma B, Christensen CL, Chipumuro E, Wong KK, Marto JA, Hammerman PS, Gray NS, George RE. Overcoming Resistance to the THZ Series of Covalent Transcriptional CDK Inhibitors. Cell Chem Biol. 2017 Dec 15. pii: S2451-9456(17)30424-5. doi: 10.1016/j.chembiol.2017.11.007. [Epub ahead of print] PubMed PMID: 29276047.

纯度：≥98%

CAS：2020052-55-3