Isotetrandrine is a novel, naturally occuring, cell-permeable and potent PLA2 inhibitor found in S. acutum. It can block NMO-IgG binding to AQP4 without affecting the expression and function of AQP4. It can also inhibit NMO-IgG binding to astrocyte AQP4 in NMO patient sera and block NMO-IgG-dependent complement-mediated cytotoxicity.

纯度：≥98%

CAS：477-57-6