Darbufelone, formerly known as CI-1004; PD-136095-0073, is COX-2 inhibitor potentially for the treatment of rheumatoid arthritis. Darbufelone also induces growth inhibition of lung cancer cells both in vitro and in vivo. References: Che XH, Chen CL, Ye XL, Weng GB, Guo XZ, Yu WY, Tao J, Chen YC, Chen X. Dual inhibition of COX-2/5-LOX blocks colon cancer proliferation, migration and invasion in vitro. Oncol Rep. 2016 Mar;35(3):1680-8. doi: 10.3892/or.2015.4506. Epub 2015 Dec 22. PubMed PMID: 26707712.

纯度：≥98%

CAS：139340-56-0