生物活性
Elacridar hydrochloride是一种P-糖蛋白抑制剂,已在体内和体外用作P-糖蛋白(Pgp)的工具抑制剂,以研究转运蛋白在处理各种测试分子中的作用。
化学数据
目录号 | A15077 |
作用机制 | Inhibitor (抑制剂) |
M. Wt | 600.1 |
Formula | C34H34ClN3O5 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 143851-98-3 |
Synonyms | GF 120918A, GF120918A, GF-120918A |
SMILES | COC1=CC=CC2=C1NC3=C(C2=O)C=CC=C3C(=O)NC4=CC=C(C=C4)CCN5CCC6=CC(=C(C=C6C5)OC)OC.Cl |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 16.66 mL | 83.32 mL | 166.64 mL |
0.5 mM | 3.33 mL | 16.66 mL | 33.33 mL |
1 mM | 1.67 mL | 8.33 mL | 16.66 mL |
5 mM | 0.33 mL | 1.67 mL | 3.33 mL |
*The above data is based on the productmolecular weight 600.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.