CB-181963, formerly known as CAB-175, is a novel cephalosporin. CB-181963 shows excellent activity against MRSA strains resistant to other cephalosporins in both planktonic and biofilm cultures.CB-181963 is a potent antistaphylococcal agent with better activity against MRSA than other cephalosporins. The anti-MRSA activity is correlated with elevated binding to PBP2a. CB-181963 may have a role in the treatment of staphylococcal infections, including those caused by MRSA and in the prophylaxis of biofilm-associated MSSA and MRSA infections. References: Burall LS, Rodolakis A, Rekiki A, Myers GS, Bavoil PM. Genomic analysis of an attenuated Chlamydia abortus live vaccine strain reveals defects in central metabolism and surface proteins. Infect Immun. 2009 Sep;77(9):4161-7. doi: 10.1128/IAI.00189-09. Epub 2009 Jul 13. PubMed PMID: 19596773; PubMed Central PMCID: PMC2738009.

纯度：≥98%

CAS：635292-67-0