DCYM21, formerly known as DC_YM21, is an inhibitor of menin-MLL interaction. DCYM21 displays potent and selective blockage of proliferation and induces both cell cycle arrest and differentiation of leukemia cells harboring MLL translocations. References: Yue L, Du J, Ye F, Chen Z, Li L, Lian F, Zhang B, Zhang Y, Jiang H, Chen K, Li Y, Zhou B, Zhang N, Yang Y, Luo C. Identification of novel small-molecule inhibitors targeting menin-MLL interaction, repurposing the antidiarrheal loperamide. Org Biomol Chem. 2016 Sep 28;14(36):8503-19. doi: 10.1039/c6ob01248e. Epub 2016 Aug 19. PubMed PMID: 27541268.

纯度：≥98%

CAS：2001072-35-9