DEAP fluoranthene, interaction with DNA and metaphase chromosomes by bind to DNA. DEAP fluoranthene shows a slight A-T preference in binding to DNA and was also found to change the topological winding number of superhelical DNA. These data, and the determined unwinding angle of 27 degree for DEAP fluoranthene, strongly support an intercalation mode of binding for this drug to DNA. References: Miller FD, Lin CC, Van de Sande JH. Interaction of DEAP fluoranthene (RMI 9563 DA) with DNA and metaphase chromosomes. J Histochem Cytochem. 1981 Aug;29(8):969-76. PubMed PMID: 7276537.

纯度：≥98%

CAS：27086-86-8