Delucemine Hydrochloride, formerly known as NPS-1506, is a glutamate receptor antagonist potentially for the treatment of major depressive disorder and stroke. Delucemine Hydrochloride is a moderate affinity antagonist that inhibits NMDA/glycine-induced increases in cytosolic calcium in cultured rat cerebellar granule cells and displaces the binding of [3H]MK-801 to rat cortical membranes. Delucemine Hydrochloride improved measures of brain tissue edema and ion homeostasis. References: Browne KD, Leoni MJ, Iwata A, Chen XH, Smith DH. Acute treatment with MgSO4 attenuates long-term hippocampal tissue loss after brain trauma in the rat. J Neurosci Res. 2004 Sep 15;77(6):878-83. PubMed PMID: 15334605.

纯度：≥98%

CAS：186495-99-8