Deltazinone is highly potent and selective PDEδ inhibitor. Deltazinone exhibits less unspecific cytotoxicity than the previously reported Deltarasin and displays a high correlation with the phenotypic effect of PDEδ knockdown in a set of human pancreatic cancer cell lines. References: Papke B, Murarka S, Vogel HA, Martín-Gago P, Kovacevic M, Truxius DC, Fansa EK, Ismail S, Zimmermann G, Heinelt K, Schultz-Fademrecht C, Al Saabi A, Baumann M, Nussbaumer P, Wittinghofer A, Waldmann H, Bastiaens PI. Identification of pyrazolopyridazinones as PDEδ inhibitors. Nat Commun. 2016 Apr 20;7:11360. doi: 10.1038/ncomms11360. PubMed PMID: 27094677; PubMed Central PMCID: PMC4843002.

纯度：≥98%

CAS：894554-89-3