BWA868C is a DP receptor-selective antagonist. It reverses the anti-aggregatory effects of DP receptor agonists in a dose-dependent manner. Likewise, BW A868C antagonizes the accumulation of cAMP in rabbit non-pigmented ciliary epithelial cells. The Ki for BW A868C is approximately 1.7 nM. References: Sharif NA, Williams GW, Davis TL. Pharmacology and autoradiography of human DP prostanoid receptors using [(3)H]-BWA868C, a DP receptor-selective antagonist radioligand. Br J Pharmacol. 2000 Nov;131(6):1025-38. PubMed PMID: 11082108; PubMed Central PMCID: PMC1572442.

纯度：≥98%

CAS：118675-50-6