Diuron is a phenylurea herbicide that inhibits photosynthesis by preventing the formation of ATP and NADH.1 It decreases total respiration in roots of wheat by 50% and ground respiration by 100% when used at a concentration of 25 nM/ml.2 Diuron (2,500 ppm, dietary) increases the incidence of urinary bladder urothelial carcinomas in male and female mice by 73 and 27%, respectively.1 It increases the production of reactive oxygen species (ROS) in MCF-7 human breast adenocarcinoma and BeWo human placental choriocarcinoma cells when used at a concentration of 200 μM and reduces viability of BeWo, but not MCF-7, cells when used at concentrations of 50 and 200 μM.3 Formulations containing diuron have been used to control broadleaf and grass weeds and as a biocidal antifouling agent. References: Huovinen M, Loikkanen J, Naarala J, Vahakangas K. Toxicity of diuron in human cancer cells. Toxicol In Vitro. 2015 Oct;29(7):1577-86. doi: 10.1016/j.tiv.2015.06.013. Epub 2015 Jun 15. PubMed PMID: 26086120.

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CAS：330-54-1