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Diclofenac
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Diclofenac图片
CAS NO:15307-86-5
规格:≥98%
包装与价格:
包装价格(元)
1g电议
5g电议
10g电议
25g电议
50g电议
100g电议

产品介绍

Diclofenac (formerly GP-45840; Voltarol; Voltaren) is a potent nonsteroidal anti-inflammatory drug (NSAID), acting as a non-selective COX inhibitor with IC50 of 0.5 μg/ml and 0.5 μg/ml for COX-1 and -2 in intact cells, respectively, used to relieve pain and reduce swelling in flammation. Diclofenac inhibits Wnt/beta-catenin signaling without altering the level of beta-catenin protein and reduces the expression of beta-catenin/TCF-dependent genes. Diclofenac induces the degradation of IkappaBalpha, which increases free nuclear factor kappaB (NF-kappaB) in colon cancer cells.

纯度:≥98%

CAS:15307-86-5