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L-745,870 trihydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:866021-03-6
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

L-745,870 Trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist. L-745,870 has Kis of 0.51, 2300 and 960 nM for D4, D3 and D2 subtypes respectively and > 1000-fold selectivity over 5-HT2, D1 and D5 receptors. References: Collins GT, Truccone A, Haji-Abdi F, Newman AH, Grundt P, Rice KC, Husbands SM, Greedy BM, Enguehard-Gueiffier C, Gueiffier A, Chen J, Wang S, Katz JL, Grandy DK, Sunahara RK, Woods JH. Proerectile effects of dopamine D2-like agonists are mediated by the D3 receptor in rats and mice. J Pharmacol Exp Ther. 2009 Apr;329(1):210-7. doi: 10.1124/jpet.108.144048. PubMed PMID: 19136638; PubMed Central PMCID: PMC2670592.

纯度:≥98%

CAS:866021-03-6