Ibodutant, formerly known as MEN-15596, is a tachykinin receptor antagonist under development for irritable bowel syndrome diarrhea. Ibodutant selectively blocks the tachykinin receptor NK2, with blockade practically complete in nanomolar concentrations. References: Bellucci F, Buéno L, Bugianesi R, Crea A, D'Aranno V, Meini S, Santicioli P, Tramontana M, Maggi CA. Gender related differential effect of tachykinin NK2 receptor-mediated visceral hyperalgesia in guinea pig colon. Br J Pharmacol. 2016 Jan 13. doi: 10.1111/bph.13427. [Epub ahead of print] PubMed PMID: 26758701.

纯度：≥98%

CAS：522664-63-7