DMI-9523, formerly known as DA-DKP; Ampion; DM-9523; DADKP, is nuclear factor NF-κB activation inhibitor potentially for the treatment of osteoarthritis. Aspartyl-alanyl- diketopiperazine (DA-DKP) is generated by cleavage and cyclization from the N-terminus of human albumin during the preparation of commercial serum albumin product. Antigen-stimulated human T lymphocytes produce significantly lower quantities of interferon-gamma and tumor necrosis factor-alpha after stimulation in vitro in the presence of DA-DKP. DA-DKP can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy. References:

纯度：≥98%

CAS：397847-46-0