Trifarotene (CD5789; trade name Aklief) is a gamma retinoic acid receptor (RAR) agonist under approved in 2019 as a topical cream for the treatment of skin disorders, including acne vulgaris, cutaneous t-cell lymphoma and lamellar ichthyosis. It has Kdapp of 2, 15 and 500 nM for RARγ, RARβ and RARα, respectively. It has Kdapp of 2, 15 and 500 nM for RARγ, RARβ and RARα, respectively.

纯度：≥98%

CAS：895542-09-3