CAS NO: | 2227996-00-9 |
包装: | 50mg, 100mg, 250mg |
规格: | ≥98% |
EG01377 is a neuropilin-1 antagonists combine anti-angiogenic and anti-tumour activity with immune modulation through reduction of transforming growth factor beta (TGFβ) production in regulatory T-cells. EG01377 showed properties suitable for further investigation. References: Powell J, Mota F, Steadman D, Soudy C, Miyauchi JT, Crosby S, Jarvis A, Reisinge T, Winfield N, Evans G, Finniear A, Yelland T, Chou YT, Chan AWE, O'Leary A, Cheng L, Liu D, Fotinou N, Milagre C, Martin JF, Jia H, Frankel P, Djordjevic S, Tsirka SE, Zachary IC, Selwood DL. Small molecule neuropilin-1 antagonists combine anti-angiogenic and anti-tumour activity with immune modulation through reduction of transforming growth factor beta (TGFβ) production in regulatory T-cells. J Med Chem. 2018 Apr 12. doi: 10.1021/acs.jmedchem.8b00210. [Epub ahead of print] PubMed PMID: 29648813.
纯度:≥98%
CAS:2227996-00-9