CAS NO: | 162706-37-8 |
规格: | ≥98% |
包装 | 价格(元) |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
LU 79553, formerly known as LU 79553, is a novel DNA intercalator with potent antitumor activity which is highly cytotoxic in vitro with EC50 (concentration required for 50% inhibition of growth) ranging from 2 x 10(-7) to 5 x 10(-10) M. LU-79553 is also a DNA-binding topoisomerase II inhibitor that is particularly effective against human solid tumors that are refractory to other drugs. References: GonzA!lez-Bulnes L, Gallego J. Indirect effects modulating the interaction between DNA and a cytotoxic bisnaphthalimide reveal a two-step binding process. J Am Chem Soc. 2009 Jun 10;131(22):7781-91. PubMed PMID: 19449871.
纯度:≥98%
CAS:162706-37-8,