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Enrasentan
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:167256-08-8
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Enrasentan, formerly known as SB-217242, is a dual receptor endothelin antagonist with a higher affinity for ET(A) receptors. In an animal model of hypertension and cardiac hypertrophy the drug has reduced blood pressure, prevented cardiac hypertrophy and preserved myocardial function. Enrasentan improves survival, limits left ventricular remodeling, and preserves myocardial performance in hypertensive cardiac hypertrophy and dysfunction. References: Prasad SK, Dargie HJ, Smith GC, Barlow MM, Grothues F, Groenning BA, Cleland JG, Pennell DJ. Comparison of the dual receptor endothelin antagonist enrasentan with enalapril in asymptomatic left ventricular systolic dysfunction: a cardiovascular magnetic resonance study. Heart. 2006 Jun;92(6):798-803. Epub 2005 Dec 9. PubMed PMID: 16339819; PubMed Central PMCID: PMC1860639.

纯度:≥98%

CAS:167256-08-8