TMC647055 (TMC-647055) is a potent HCV NS5B polymerase inhibitor with the potential to be used for the treatment of HCV infection. TMC647055 has nanomolar cellular potency (EC(50) of 82 nM) with minimal associated cell toxicity (CC(50)>20 μM) and promising pharmacokinetic profiles in rats and dogs. TMC647055 showed promising in vitro bioactive compound, kinetic, and virological profile that is currently undergoing clinical evaluation. TMC647055 is currently being evaluated in clinical trials.

纯度：≥98%

CAS：1204416-97-6