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Esketamine HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:33643-47-9
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Esketamine HCl, formerly known as JNJ-54135419 or (S)-(+)-Ketamine, is a dopamine reuptake inhibitor potentially for the treatment of depression. Ketamine is an NMDA receptor channel blocker (Ki = 1.2-2.5 μM, IC50 = 3.2-6.1 μM). Esketamine is about 4 times more potent an analgesic than the R-enantiomer, and twice as potent as the racemic mixture. Esketamine HCl is discontinued (DEA controlled substance). References: Malhi GS, Byrow Y, Cassidy F, Cipriani A, Demyttenaere K, Frye MA, Gitlin M, Kennedy SH, Ketter TA, Lam RW, McShane R, Mitchell AJ, Ostacher MJ, Rizvi SJ, Thase ME, Tohen M. Ketamine: stimulating antidepressant treatment? BJPsych Open. 2016 May 11;2(3):e5-e9. PubMed PMID: 27703782.

纯度:≥98%

CAS:33643-47-9