MK-940 is a potential central nervous system agent and an anti-depressant. References: Verdurand M, Nguyen V, Stark D, Zahra D, Gregoire MC, Greguric I, Zavitsanou K. Comparison of Cannabinoid CB(1) Receptor Binding in Adolescent and Adult Rats: A Positron Emission Tomography Study Using [F]MK-9470. Int J Mol Imaging. 2011;201548123. doi: 10.1155/2011/548123. Epub 2011 Dec 11. PubMed PMID: 22187642; PubMed Central PMCID: PMC3236487. 2: Gannon P, Itil T, Keskiner A, Hsu B. Clinical and quantitative electroencephalographical effects of MK 940. Arzneimittelforschung. 1970 Jul;20(7):971-4. PubMed PMID: 4918922. 3: Amoozegar MA, Makhdoumi-Kakhki A, Mehrshad M, Fazeli SA, Sproer C, Ventosa A. Halorientalis persicus sp. nov., an extremely halophilic archaeon isolated from a salt lake and emended description of the genus Halorientalis. Int J Syst Evol Microbiol. 2014 Mar;64(Pt 3):940-4. doi: 10.1099/ijs.0.058164-0. Epub 2013 Dec 18. PubMed PMID: 24425819. 4: Finster KW, Cockell CS, Voytek MA, Gronstal AL, Kjeldsen KU. Description of Tessaracoccus profundi sp.nov., a deep-subsurface actinobacterium isolated from a Chesapeake impact crater drill core (940 m depth). Antonie Van Leeuwenhoek. 2009 Nov;96(4):515-26. doi: 10.1007/s10482-009-9367-y. Epub 2009 Aug 8. PubMed PMID: 19669589. 5: Xu M, Qiang F, Gao Y, Kang M, Wang M, Tao G, Gong W, Zhu H, Wu D, Zhang Z, Zhao Q. Evaluation of a novel functional single-nucleotide polymorphism (rs35010275 G>C) in MIR196A2 promoter region as a risk factor of gastric cancer in a Chinese population. Medicine (Baltimore). 2014 Nov;93(26):e173. doi: 10.1097/MD.0000000000000173. PubMed PMID: 25474430; PubMed Central PMCID: PMC4616385. 6: Ankermann T, Reisner A, Wiemann T, Koehler H, Krams M, Krause MF. Intrapulmonary application of a 5-lipoxygenase inhibitor using surfactant as a carrier reduces lung edema in a piglet model of airway lavage. Pediatr Pulmonol. 2006 May;41(5):452-62. PubMed PMID: 16547963. 7: Sommer C, Schomacher M, Berger C, Kuhnert K, Müller HD, Schwab S, Schabitz WR. Neuroprotective cannabinoid receptor antagonist SR141716A prevents downregulation of excitotoxic NMDA receptors in the ischemic penumbra. Acta Neuropathol. 2006 Sep;112(3):277-86. Epub 2006 Jul 27. PubMed PMID: 16871404. 8: Qussi B, Suess WG. Investigation of the effect of various shellac coating compositions containing different water-soluble polymers on in vitro drug release. Drug Dev Ind Pharm. 2005 Jan;31(1):99-108. PubMed PMID: 15704861. 9: Melis MR, Succu S, Mascia MS, Argiolas A. Antagonism of cannabinoid CB1 receptors in the paraventricular nucleus of male rats induces penile erection. Neurosci Lett. 2004 Apr 8;359(1-2):17-20. PubMed PMID: 15050701. 10: Carswell HV, Graham DI, Stone TW. Kainate-evoked release of adenosine from the hippocampus of the anaesthetised rat: possible involvement of free radicals. J Neurochem. 1997 Jan;68(1):240-7. PubMed PMID: 8978731. 1 Bauer VJ, Duffy BJ, Hoffman D, Klioze SS, Kosley RW Jr, McFadden AR, Martin LL, Ong HH. Synthesis of spiro[isobenzofuran-1(3H),4'-piperidines] as potential central nervous system agents. J Med Chem. 1976 Nov;19(11):1315-24. PubMed PMID: 1003409. 12: Gill R, Alanine A, Bourson A, Buttelmann B, Fischer G, Heitz MP, Kew JN, Levet-Trafit B, Lorez HP, Malherbe P, Miss MT, Mutel V, Pinard E, Roever S, Schmitt M, Trube G, Wybrecht R, Wyler R, Kemp JA. Pharmacological characterization of Ro 63-1908 (1-[2-(4-hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol), a novel subtype-selective N-methyl-D-aspartate antagonist. J Pharmacol Exp Ther. 2002 Sep;302(3):940-8. PubMed PMID: 12183650. 13: Yenny, Nafrialdi, Djoerban Z, Setiabudy R. Pharmacokinetic interaction between efavirenz and rifampicin in healthy volunteers. Int J Clin Pharmacol Ther. 2011 Feb;49(2):162-8. PubMed PMID: 21255533. 14: Alabakovska SB, Labudovic DD, Tosheska KN, Todorova BB. Low density lipoprotein particle size phenotyping in healthy persons and patients with myocardial infarction. Croat Med J. 2002 Jun;43(3):290-5. PubMed PMID: 12035134.

纯度：≥98%

CAS：5154-92-7