Flumorph is novel fungicide, disturbing the polar deposition of newly synthesized cell wall materials during cystospore germination and hyphal growth. Flumorph did not inhibit the synthesis of cell wall materials, but disturbed the polar deposition of newly synthesized cell wall materials during cystospore germination and hyphal growth. In flumorph-treated hyphae, the most characteristic change was the development of periodic swelling ("beaded" morphology) and the disruption of tip growth. Upon removing flumorph, normal tip growth and organized F-actin were observed again. Flumorph had induced systemic genotoxicity in mammals as it caused DNA damage in all tested vital organs, especially in brain and spleen. References: Guan A, Wang M, Yang J, Wang L, Xie Y, Lan J, Liu C. Discovery of a New Fungicide Candidate through Lead Optimization of Pyrimidinamine Derivatives and Its Activity against Cucumber Downy Mildew. J Agric Food Chem. 2017 Dec 13;65(49):10829-10835. doi: 10.1021/acs.jafc.7b03898. Epub 2017 Nov 30. PubMed PMID: 29151354.

纯度：≥98%

CAS：211867-47-9