Fluorizoline is a first-in-class inducer of p53-independent apoptosis in a wide range of tumor cell lines. It directly binds to prohibitin 1 and 2 (PHBs), two proteins involved in the regulation of several cellular processes, including apoptosis. References: Wierz M, Pierson S, Chouha N, Désaubry L, Francois JH, Berchem G, Paggetti J, Moussay E. The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells ex vivo but fails to prevent leukemia development in a murine model. Haematologica. 2018 Jan 5. pii: haematol.2017.175349. doi: 10.3324/haematol.2017.175349. [Epub ahead of print] PubMed PMID: 29305413.

纯度：≥98%

CAS：1362243-70-6