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TES-1025
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1883602-21-8
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

TES-1025 is the first potent and selective inhibitor of human ACMSD (IC50 = 0.013 μM) that increases NAD+ levels in cellular systems. Defects in NAD+ homeostasis underpin a wide range of diseases, including cancer, metabolic disorders, and aging. References: Pellicciari R, Liscio P, Giacchè N, De Franco F, Carotti A, Robertson J, Cialabrini L, Katsyuba E, Raffaelli N, Auwerx J. α-Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of De Novo Nicotinamide Adenine Dinucleotide (NAD(+)) Biosynthesis. J Med Chem. 2018 Jan 26. doi: 10.1021/acs.jmedchem.7b01254. [Epub ahead of print] PubMed PMID: 29345930.

纯度:≥98%

CAS:1883602-21-8