您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Nebicapone
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Nebicapone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:274925-86-9
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Nebicapone, formerly known as BIA-3202, is a catechol-O-methyltransferase inhibitor potentially for the treatment of Parkinson's disease. Nebicapone dose dependently and significantly decreased COMT activity. Nebicapone also increased systemic exposure to levodopa and improved motor response. References: Bicker J, Alves G, Fortuna A, Soares-da-Silva P, Falcao A. A new PAMPA model using an in-house brain lipid extract for screening the blood-brain barrier permeability of drug candidates. Int J Pharm. 2016 Mar 30;501(1-2):102-11. doi: 10.1016/j.ijpharm.2016.01.074. PubMed PMID: 26836708.

纯度:≥98%

CAS:274925-86-9