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G-5555
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1648863-90-4
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

G-5555 is a potent and selective PAK1 inhibitor. G-5555 showed excellent kinase selectivity and inhibited only eight out of the 235 kinases tested other than PAK1 with inhibition >70%: PAK2, PAK3, KHS1, Lck, MST3, MST4, SIK2, and YSK1. G-5555 demonstrated in vivo PK/PD effects consistent with the observed potency and pharmacokinetic properties. G-5555 may be a potential cancer drug candidate. The p21-activated kinases (PAKs), which belong to the sterile-20 (STE20) family of kinases, play important roles in the regulation of key cellular phenomena including cell migration, proliferation, and survival mechanisms. References:

纯度:≥98%

CAS:1648863-90-4