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Gacyclidine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:68134-81-6
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Gacyclidine, formerly known as OTO-311 and GK-11, is a N-methyl-D-aspartate (NMDA) receptor antagonist potentially for the treatment of tinnitus. Local administration of gacyclidine to the cochlea can suppress salicylate-induced tinnitus. Tritiated gacyclidine and its enantiomers bind to NMDA receptors with binding parameters similar to those of other non-competitive NMDA receptor antagonists. References: Chenoweth JA, Gerona RR, Ford JB, Sutter ME, Rose JS, Albertson TE, Clarke SO, Owen KP. Altered mental status and end organ damage associated with the use of gacyclidine: a case series. J Med Toxicol. 2015 Mar;11(1):115-20. doi: 10.1007/s13181-014-0415-2. PubMed PMID: 25048606; PubMed Central PMCID: PMC4371039.

纯度:≥98%

CAS:68134-81-6