Description: Ganciclovir sodium, anacyclovir analog, is a novel and potent antiviral drug used to treat or prevent cytomegalovirus (CMV) infections. Ganciclovir (2'-Nor-2'-deoxyguanosine, BW-759) is a novel and potent herpes simplex virus (HSV) inhibitor. It is a synthetic analog of 2'-deoxy-guanosineused to treat or prevent cytomegalovirus (CMV) infections. It acts by inhibiting the replication of human CMV with an IC50 value of 0.01 μM and is effective against strains of CMV from human, monkey, mouse, and guinea pig.

References:

[1]. Management of cytomegalovirus disease with antiviral drugs. Rev.Infect.Dis. 12(Suppl. 7), S849-S860 (1990).

[2]. Antiviral therapy: Current concepts and practices. Clin.Microbiol.Rev. 5(2), 146-182 (1992).