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Finerenone(BAY94-8862)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Finerenone(BAY94-8862)图片
CAS NO:1050477-31-0
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议
1g电议

产品介绍

Finerenone (formerly known as BAY94-8862; BAY-948862; Kerendia) is a potent, selective, and orally bioavailable non-steroidal anti-mineralocorticoid or mineralocorticoid receptor (MR) antagonist (IC50 = 18 nM) that was approved in July 2021 by the US FDA to reduce the risk of kidney and heart complications in chronic kidney disease associated with type 2 diabetes. It was in phase III clinical trials for the treatment of chronic heart failure since October 2015. Finerenone has less relative affinity to other steroid hormone receptors than currently available antimineralocorticoids such as eplerenone and spironolactone, which should result in fewer adverse effects like gynaecomastia, impotence, and low sex drive.

纯度:≥98%

CAS:1050477-31-0