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TBCA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:934358-00-6
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

TBCA, formerly known as tetrabromocinnamic acid, is a potent CK2 inhibitor. TBCA inhibits CK2 five times more efficiently than TBB (IC50 0.11 and 0.56 microM, respectively), without having any comparable effect on DYRK1 a (IC50 24.5 microM) or on a panel of 28 protein kinases. The usefulness of TBCA for cellular studies has been validated by showing that it reduces the viability of Jurkat cells more efficiently than TBB through enhancement of apoptosis. References: Lee HR, Shin HK, Park SY, Kim HY, Lee WS, Rhim BY, Hong KW, Kim CD. Attenuation of β-amyloid-induced tauopathy via activation of CK2α/SIRT Targeting for cilostazol. J Neurosci Res. 2014 Feb;92(2):206-17. doi: 10.1002/jnr.23310. Epub 2013 Nov 19. PubMed PMID: 24254769.

纯度:≥98%

CAS:934358-00-6