Olprinone (INN) is a cardiotonic agent and a specific phosphodiesterase (PDE)-III inhibitor. It has been marketed in Japan since 1996. Olprinone attenuates excessive shear stress through up-regulation of endothelial nitric oxide synthase in a rat excessive hepatectomy model. Olprinone reduces the development of multiple organ dysfunction syndrome in mice. References: Endo R, Kurata Y, Notsu T, Li P, Morikawa K, Kondo T, Ogura K, Miake J, Yoshida A, Shirayoshi Y, Ninomiya H, Higaki K, Kuwabara M, Yamamoto K, Inagaki Y, Hisatome I. Stabilization of Kv1.5 channel protein by the inotropic agent olprinone. Eur J Pharmacol. 2015 Oct 15;765:488-94. doi: 10.1016/j.ejphar.2015.09.013. Epub 2015 Sep 12. PubMed PMID: 26368666.

纯度：≥98%

CAS：119615-63-3