TAP311 is a novel, piperidine-based inhibitor of cholesteryl ester transfer protein (CETP). It has a core structure distinct from other reported CETP inhibitors. CETP inhibitors have therapeutic potential against coronary heart disease as they mediate chemical exchange involving cholesterol. TAP311 has a limited lipophilicity, improving pharmacological profile. It is under clinical trials. References:

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CAS：1149362-88-8