GSK 189254A is histamine H3 receptor antagonist for the treatment of narcolepsy. The compound may also be useful in the treatment of dementia and neuropathic pain. Histamine H3 receptor antagonists have been shown to increase the release of neurotransmitters in the brain and to enhance cognition in vivo. References: Schou M, Varnas K, Jureus A, Ahlgren C, Malmquist J, Haggkvist J, Tari L, Wesolowski SS, Throner SR, Brown DG, Nilsson M, Johnstrom P, Finnema SJ, Nakao R, Amini N, Takano A, Farde L. Discovery and Preclinical Validation of [(11)C]AZ13153556, a Novel Probe for the Histamine Type 3 Receptor. ACS Chem Neurosci. 2016 Feb 17;7(2):177-84. doi: 10.1021/acschemneuro.5b00268. Epub 2015 Nov 30. PubMed PMID: 26529287.

纯度：≥98%

CAS：945493-87-8