Diazaborine, formerly known as SA 84474, is a chemical compound that inhibits maturation of rRNAs for the large ribosomal subunit. Diazaborine blocks ribosome biogenesis by inhibiting the AAA-ATPase Drg1. Diazaborine treatment causes, within minutes, a rapid redistribution of the protein from the nucleolus to the periphery of the nucleus, which provides a possible explanation for the effect of diazaborine on rRNA processing. References: Bandyopadhyay A, Cambray S, Gao J. Fast Diazaborine Formation of Semicarbazide Enables Facile Labeling of Bacterial Pathogens. J Am Chem Soc. 2017 Jan 18;139(2):871-878. doi: 10.1021/jacs.6b11115. PubMed PMID: 27992180.

纯度：≥98%

CAS：22959-81-5